AustralieFrV1, PubMed, Curation, bibRecord, 002056

Membrane-anchored Serine Protease Matriptase Is a Trigger of Pulmonary Fibrogenesis.

Identifieur interne : 002056 ( PubMed/Curation ); précédent : 002055; suivant : 002057

Membrane-anchored Serine Protease Matriptase Is a Trigger of Pulmonary Fibrogenesis.

Auteurs : Olivier Bardou [France] ; Awen Menou [France] ; Charlène François [France] ; Jan Willem Duitman [Pays-Bas] ; Jan H. Von Der Thüsen [Pays-Bas] ; Raphaël Borie [France] ; Katiuchia Uzzun Sales [États-Unis] ; Kathrin Mutze [Allemagne] ; Yves Castier [France] ; Edouard Sage ; Ligong Liu [Australie] ; Thomas H. Bugge [États-Unis] ; David P. Fairlie [Australie] ; Mélanie Königshoff [Allemagne] ; Bruno Crestani [France] ; Keren S. Borensztajn [France]

Source :

American journal of respiratory and critical care medicine [ 1535-4970 ] ; 2016.

RBID : pubmed:26599507

Descripteurs français

KwdFr :
- Adulte d'âge moyen, Animaux, Femelle, Fibrose pulmonaire idiopathique (métabolisme), Fibrose pulmonaire idiopathique (physiopathologie), Humains, Modèles animaux de maladie humaine, Mâle, Poumon (métabolisme), Poumon (physiopathologie), Protéases à sérine (métabolisme), Réaction de polymérisation en chaîne, Serine endopeptidases (métabolisme), Souris, Souris de lignée C57BL, Technique de Western.
MESH :
- métabolisme : Fibrose pulmonaire idiopathique, Poumon, Protéases à sérine, Serine endopeptidases.
- physiopathologie : Fibrose pulmonaire idiopathique, Poumon.
- Adulte d'âge moyen, Animaux, Femelle, Humains, Modèles animaux de maladie humaine, Mâle, Réaction de polymérisation en chaîne, Souris, Souris de lignée C57BL, Technique de Western.

English descriptors

KwdEn :
- Animals, Blotting, Western, Disease Models, Animal, Female, Humans, Idiopathic Pulmonary Fibrosis (metabolism), Idiopathic Pulmonary Fibrosis (physiopathology), Lung (metabolism), Lung (physiopathology), Male, Mice, Mice, Inbred C57BL, Middle Aged, Polymerase Chain Reaction, Serine Endopeptidases (metabolism), Serine Proteases (metabolism).
MESH :
- chemical , metabolism : Serine Endopeptidases, Serine Proteases.
- metabolism : Idiopathic Pulmonary Fibrosis, Lung.
- physiopathology : Idiopathic Pulmonary Fibrosis, Lung.
- Animals, Blotting, Western, Disease Models, Animal, Female, Humans, Male, Mice, Mice, Inbred C57BL, Middle Aged, Polymerase Chain Reaction.

Abstract

Idiopathic pulmonary fibrosis (IPF) is a devastating disease that remains refractory to current therapies.

DOI: 10.1164/rccm.201502-0299OC
PubMed: 26599507

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002081

Links to Exploration step

pubmed:26599507

Curation

No country items

Edouard Sage

<affiliation><nlm:affiliation>10 Department of Thoracic Surgery and Lung Transplantation, Hôpital Foch, Suresnes, France; and.</nlm:affiliation>
<wicri:noCountry code="subField">France; and</wicri:noCountry>
</affiliation>

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Membrane-anchored Serine Protease Matriptase Is a Trigger of Pulmonary Fibrogenesis.</title>
<author><name sortKey="Bardou, Olivier" sort="Bardou, Olivier" uniqKey="Bardou O" first="Olivier" last="Bardou">Olivier Bardou</name>
<affiliation wicri:level="1"><nlm:affiliation>1 Inserm UMR1152, Medical School Xavier Bichat, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>1 Inserm UMR1152, Medical School Xavier Bichat, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Menou, Awen" sort="Menou, Awen" uniqKey="Menou A" first="Awen" last="Menou">Awen Menou</name>
<affiliation wicri:level="1"><nlm:affiliation>1 Inserm UMR1152, Medical School Xavier Bichat, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>1 Inserm UMR1152, Medical School Xavier Bichat, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Francois, Charlene" sort="Francois, Charlene" uniqKey="Francois C" first="Charlène" last="François">Charlène François</name>
<affiliation wicri:level="1"><nlm:affiliation>1 Inserm UMR1152, Medical School Xavier Bichat, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>1 Inserm UMR1152, Medical School Xavier Bichat, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Duitman, Jan Willem" sort="Duitman, Jan Willem" uniqKey="Duitman J" first="Jan Willem" last="Duitman">Jan Willem Duitman</name>
<affiliation wicri:level="1"><nlm:affiliation>3 Center for Experimental and Molecular Medicine, Academic Medical Center, Amsterdam, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>3 Center for Experimental and Molecular Medicine, Academic Medical Center, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Von Der Thusen, Jan H" sort="Von Der Thusen, Jan H" uniqKey="Von Der Thusen J" first="Jan H" last="Von Der Thüsen">Jan H. Von Der Thüsen</name>
<affiliation wicri:level="1"><nlm:affiliation>4 Department of Pathology, Erasmus Medical Centre, Rotterdam, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>4 Department of Pathology, Erasmus Medical Centre, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Borie, Raphael" sort="Borie, Raphael" uniqKey="Borie R" first="Raphaël" last="Borie">Raphaël Borie</name>
<affiliation wicri:level="1"><nlm:affiliation>2 Université Paris Diderot, Sorbonne Paris Cité, Département Hospitalo-universitaire FIRE (Fibrosis, Inflammation and Remodeling) and LabEx Inflamex, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>2 Université Paris Diderot, Sorbonne Paris Cité, Département Hospitalo-universitaire FIRE (Fibrosis, Inflammation and Remodeling) and LabEx Inflamex, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sales, Katiuchia Uzzun" sort="Sales, Katiuchia Uzzun" uniqKey="Sales K" first="Katiuchia Uzzun" last="Sales">Katiuchia Uzzun Sales</name>
<affiliation wicri:level="2"><nlm:affiliation>6 Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>6 Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Mutze, Kathrin" sort="Mutze, Kathrin" uniqKey="Mutze K" first="Kathrin" last="Mutze">Kathrin Mutze</name>
<affiliation wicri:level="1"><nlm:affiliation>8 Member of the German Center of Lung Research, Comprehensive Pneumology Center, University Hospital, Ludwig-Maximilians University, Helmholtz Zentrum München, Munich, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>8 Member of the German Center of Lung Research, Comprehensive Pneumology Center, University Hospital, Ludwig-Maximilians University, Helmholtz Zentrum München, Munich</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Castier, Yves" sort="Castier, Yves" uniqKey="Castier Y" first="Yves" last="Castier">Yves Castier</name>
<affiliation wicri:level="1"><nlm:affiliation>9 Assistance Publique-Hôpitaux de Paris, Department of Vascular and Thoracic Surgery, Bichat-Claude Bernard University Hospital, Denis Diderot University and Medical School Paris VII, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>9 Assistance Publique-Hôpitaux de Paris, Department of Vascular and Thoracic Surgery, Bichat-Claude Bernard University Hospital, Denis Diderot University and Medical School Paris VII</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sage, Edouard" sort="Sage, Edouard" uniqKey="Sage E" first="Edouard" last="Sage">Edouard Sage</name>
<affiliation><nlm:affiliation>10 Department of Thoracic Surgery and Lung Transplantation, Hôpital Foch, Suresnes, France; and.</nlm:affiliation>
<wicri:noCountry code="subField">France; and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Liu, Ligong" sort="Liu, Ligong" uniqKey="Liu L" first="Ligong" last="Liu">Ligong Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>11 Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>11 Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bugge, Thomas H" sort="Bugge, Thomas H" uniqKey="Bugge T" first="Thomas H" last="Bugge">Thomas H. Bugge</name>
<affiliation wicri:level="2"><nlm:affiliation>6 Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>6 Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Fairlie, David P" sort="Fairlie, David P" uniqKey="Fairlie D" first="David P" last="Fairlie">David P. Fairlie</name>
<affiliation wicri:level="1"><nlm:affiliation>11 Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>11 Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Konigshoff, Melanie" sort="Konigshoff, Melanie" uniqKey="Konigshoff M" first="Mélanie" last="Königshoff">Mélanie Königshoff</name>
<affiliation wicri:level="1"><nlm:affiliation>8 Member of the German Center of Lung Research, Comprehensive Pneumology Center, University Hospital, Ludwig-Maximilians University, Helmholtz Zentrum München, Munich, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>8 Member of the German Center of Lung Research, Comprehensive Pneumology Center, University Hospital, Ludwig-Maximilians University, Helmholtz Zentrum München, Munich</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Crestani, Bruno" sort="Crestani, Bruno" uniqKey="Crestani B" first="Bruno" last="Crestani">Bruno Crestani</name>
<affiliation wicri:level="1"><nlm:affiliation>1 Inserm UMR1152, Medical School Xavier Bichat, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>1 Inserm UMR1152, Medical School Xavier Bichat, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Borensztajn, Keren S" sort="Borensztajn, Keren S" uniqKey="Borensztajn K" first="Keren S" last="Borensztajn">Keren S. Borensztajn</name>
<affiliation wicri:level="1"><nlm:affiliation>1 Inserm UMR1152, Medical School Xavier Bichat, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>1 Inserm UMR1152, Medical School Xavier Bichat, Paris</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2016">2016</date>
<idno type="RBID">pubmed:26599507</idno>
<idno type="pmid">26599507</idno>
<idno type="doi">10.1164/rccm.201502-0299OC</idno>
<idno type="wicri:Area/PubMed/Corpus">002081</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002081</idno>
<idno type="wicri:Area/PubMed/Curation">002056</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002056</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Membrane-anchored Serine Protease Matriptase Is a Trigger of Pulmonary Fibrogenesis.</title>
<author><name sortKey="Bardou, Olivier" sort="Bardou, Olivier" uniqKey="Bardou O" first="Olivier" last="Bardou">Olivier Bardou</name>
<affiliation wicri:level="1"><nlm:affiliation>1 Inserm UMR1152, Medical School Xavier Bichat, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>1 Inserm UMR1152, Medical School Xavier Bichat, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Menou, Awen" sort="Menou, Awen" uniqKey="Menou A" first="Awen" last="Menou">Awen Menou</name>
<affiliation wicri:level="1"><nlm:affiliation>1 Inserm UMR1152, Medical School Xavier Bichat, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>1 Inserm UMR1152, Medical School Xavier Bichat, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Francois, Charlene" sort="Francois, Charlene" uniqKey="Francois C" first="Charlène" last="François">Charlène François</name>
<affiliation wicri:level="1"><nlm:affiliation>1 Inserm UMR1152, Medical School Xavier Bichat, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>1 Inserm UMR1152, Medical School Xavier Bichat, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Duitman, Jan Willem" sort="Duitman, Jan Willem" uniqKey="Duitman J" first="Jan Willem" last="Duitman">Jan Willem Duitman</name>
<affiliation wicri:level="1"><nlm:affiliation>3 Center for Experimental and Molecular Medicine, Academic Medical Center, Amsterdam, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>3 Center for Experimental and Molecular Medicine, Academic Medical Center, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Von Der Thusen, Jan H" sort="Von Der Thusen, Jan H" uniqKey="Von Der Thusen J" first="Jan H" last="Von Der Thüsen">Jan H. Von Der Thüsen</name>
<affiliation wicri:level="1"><nlm:affiliation>4 Department of Pathology, Erasmus Medical Centre, Rotterdam, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>4 Department of Pathology, Erasmus Medical Centre, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Borie, Raphael" sort="Borie, Raphael" uniqKey="Borie R" first="Raphaël" last="Borie">Raphaël Borie</name>
<affiliation wicri:level="1"><nlm:affiliation>2 Université Paris Diderot, Sorbonne Paris Cité, Département Hospitalo-universitaire FIRE (Fibrosis, Inflammation and Remodeling) and LabEx Inflamex, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>2 Université Paris Diderot, Sorbonne Paris Cité, Département Hospitalo-universitaire FIRE (Fibrosis, Inflammation and Remodeling) and LabEx Inflamex, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sales, Katiuchia Uzzun" sort="Sales, Katiuchia Uzzun" uniqKey="Sales K" first="Katiuchia Uzzun" last="Sales">Katiuchia Uzzun Sales</name>
<affiliation wicri:level="2"><nlm:affiliation>6 Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>6 Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Mutze, Kathrin" sort="Mutze, Kathrin" uniqKey="Mutze K" first="Kathrin" last="Mutze">Kathrin Mutze</name>
<affiliation wicri:level="1"><nlm:affiliation>8 Member of the German Center of Lung Research, Comprehensive Pneumology Center, University Hospital, Ludwig-Maximilians University, Helmholtz Zentrum München, Munich, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>8 Member of the German Center of Lung Research, Comprehensive Pneumology Center, University Hospital, Ludwig-Maximilians University, Helmholtz Zentrum München, Munich</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Castier, Yves" sort="Castier, Yves" uniqKey="Castier Y" first="Yves" last="Castier">Yves Castier</name>
<affiliation wicri:level="1"><nlm:affiliation>9 Assistance Publique-Hôpitaux de Paris, Department of Vascular and Thoracic Surgery, Bichat-Claude Bernard University Hospital, Denis Diderot University and Medical School Paris VII, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>9 Assistance Publique-Hôpitaux de Paris, Department of Vascular and Thoracic Surgery, Bichat-Claude Bernard University Hospital, Denis Diderot University and Medical School Paris VII</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sage, Edouard" sort="Sage, Edouard" uniqKey="Sage E" first="Edouard" last="Sage">Edouard Sage</name>
<affiliation><nlm:affiliation>10 Department of Thoracic Surgery and Lung Transplantation, Hôpital Foch, Suresnes, France; and.</nlm:affiliation>
<wicri:noCountry code="subField">France; and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Liu, Ligong" sort="Liu, Ligong" uniqKey="Liu L" first="Ligong" last="Liu">Ligong Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>11 Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>11 Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bugge, Thomas H" sort="Bugge, Thomas H" uniqKey="Bugge T" first="Thomas H" last="Bugge">Thomas H. Bugge</name>
<affiliation wicri:level="2"><nlm:affiliation>6 Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>6 Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Fairlie, David P" sort="Fairlie, David P" uniqKey="Fairlie D" first="David P" last="Fairlie">David P. Fairlie</name>
<affiliation wicri:level="1"><nlm:affiliation>11 Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>11 Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Konigshoff, Melanie" sort="Konigshoff, Melanie" uniqKey="Konigshoff M" first="Mélanie" last="Königshoff">Mélanie Königshoff</name>
<affiliation wicri:level="1"><nlm:affiliation>8 Member of the German Center of Lung Research, Comprehensive Pneumology Center, University Hospital, Ludwig-Maximilians University, Helmholtz Zentrum München, Munich, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>8 Member of the German Center of Lung Research, Comprehensive Pneumology Center, University Hospital, Ludwig-Maximilians University, Helmholtz Zentrum München, Munich</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Crestani, Bruno" sort="Crestani, Bruno" uniqKey="Crestani B" first="Bruno" last="Crestani">Bruno Crestani</name>
<affiliation wicri:level="1"><nlm:affiliation>1 Inserm UMR1152, Medical School Xavier Bichat, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>1 Inserm UMR1152, Medical School Xavier Bichat, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Borensztajn, Keren S" sort="Borensztajn, Keren S" uniqKey="Borensztajn K" first="Keren S" last="Borensztajn">Keren S. Borensztajn</name>
<affiliation wicri:level="1"><nlm:affiliation>1 Inserm UMR1152, Medical School Xavier Bichat, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>1 Inserm UMR1152, Medical School Xavier Bichat, Paris</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">American journal of respiratory and critical care medicine</title>
<idno type="eISSN">1535-4970</idno>
<imprint><date when="2016" type="published">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Blotting, Western</term>
<term>Disease Models, Animal</term>
<term>Female</term>
<term>Humans</term>
<term>Idiopathic Pulmonary Fibrosis (metabolism)</term>
<term>Idiopathic Pulmonary Fibrosis (physiopathology)</term>
<term>Lung (metabolism)</term>
<term>Lung (physiopathology)</term>
<term>Male</term>
<term>Mice</term>
<term>Mice, Inbred C57BL</term>
<term>Middle Aged</term>
<term>Polymerase Chain Reaction</term>
<term>Serine Endopeptidases (metabolism)</term>
<term>Serine Proteases (metabolism)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Animaux</term>
<term>Femelle</term>
<term>Fibrose pulmonaire idiopathique (métabolisme)</term>
<term>Fibrose pulmonaire idiopathique (physiopathologie)</term>
<term>Humains</term>
<term>Modèles animaux de maladie humaine</term>
<term>Mâle</term>
<term>Poumon (métabolisme)</term>
<term>Poumon (physiopathologie)</term>
<term>Protéases à sérine (métabolisme)</term>
<term>Réaction de polymérisation en chaîne</term>
<term>Serine endopeptidases (métabolisme)</term>
<term>Souris</term>
<term>Souris de lignée C57BL</term>
<term>Technique de Western</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Serine Endopeptidases</term>
<term>Serine Proteases</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Idiopathic Pulmonary Fibrosis</term>
<term>Lung</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Fibrose pulmonaire idiopathique</term>
<term>Poumon</term>
<term>Protéases à sérine</term>
<term>Serine endopeptidases</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Fibrose pulmonaire idiopathique</term>
<term>Poumon</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Idiopathic Pulmonary Fibrosis</term>
<term>Lung</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Blotting, Western</term>
<term>Disease Models, Animal</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Mice</term>
<term>Mice, Inbred C57BL</term>
<term>Middle Aged</term>
<term>Polymerase Chain Reaction</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Animaux</term>
<term>Femelle</term>
<term>Humains</term>
<term>Modèles animaux de maladie humaine</term>
<term>Mâle</term>
<term>Réaction de polymérisation en chaîne</term>
<term>Souris</term>
<term>Souris de lignée C57BL</term>
<term>Technique de Western</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Idiopathic pulmonary fibrosis (IPF) is a devastating disease that remains refractory to current therapies.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26599507</PMID>
<DateCreated><Year>2016</Year>
<Month>04</Month>
<Day>16</Day>
</DateCreated>
<DateCompleted><Year>2016</Year>
<Month>08</Month>
<Day>31</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>04</Month>
<Day>15</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1535-4970</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>193</Volume>
<Issue>8</Issue>
<PubDate><Year>2016</Year>
<Month>Apr</Month>
<Day>15</Day>
</PubDate>
</JournalIssue>
<Title>American journal of respiratory and critical care medicine</Title>
<ISOAbbreviation>Am. J. Respir. Crit. Care Med.</ISOAbbreviation>
</Journal>
<ArticleTitle>Membrane-anchored Serine Protease Matriptase Is a Trigger of Pulmonary Fibrogenesis.</ArticleTitle>
<Pagination><MedlinePgn>847-60</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1164/rccm.201502-0299OC</ELocationID>
<Abstract><AbstractText Label="RATIONALE" NlmCategory="BACKGROUND">Idiopathic pulmonary fibrosis (IPF) is a devastating disease that remains refractory to current therapies.</AbstractText>
<AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">To characterize the expression and activity of the membrane-anchored serine protease matriptase in IPF in humans and unravel its potential role in human and experimental pulmonary fibrogenesis.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Matriptase expression was assessed in tissue specimens from patients with IPF versus control subjects using quantitative reverse transcriptase-polymerase chain reaction, immunohistochemistry, and Western blotting, while matriptase activity was monitored by fluorogenic substrate cleavage. Matriptase-induced fibroproliferative responses and the receptor involved were characterized in human primary pulmonary fibroblasts by Western blot, viability, and migration assays. In the murine model of bleomycin-induced pulmonary fibrosis, the consequences of matriptase depletion, either by using the pharmacological inhibitor camostat mesilate (CM), or by genetic down-regulation using matriptase hypomorphic mice, were characterized by quantification of secreted collagen and immunostainings.</AbstractText>
<AbstractText Label="MEASUREMENTS AND MAIN RESULTS" NlmCategory="RESULTS">Matriptase expression and activity were up-regulated in IPF and bleomycin-induced pulmonary fibrosis. In cultured human pulmonary fibroblasts, matriptase expression was significantly induced by transforming growth factor-β. Furthermore, matriptase elicited signaling via protease-activated receptor-2 (PAR-2), and promoted fibroblast activation, proliferation, and migration. In the experimental bleomycin model, matriptase depletion, by the pharmacological inhibitor CM or by genetic down-regulation, diminished lung injury, collagen production, and transforming growth factor-β expression and signaling.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">These results implicate increased matriptase expression and activity in the pathogenesis of pulmonary fibrosis in human IPF and in an experimental mouse model. Overall, targeting matriptase, or treatment by CM, which is already in clinical use for other diseases, may represent potential therapies for IPF.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bardou</LastName>
<ForeName>Olivier</ForeName>
<Initials>O</Initials>
<AffiliationInfo><Affiliation>1 Inserm UMR1152, Medical School Xavier Bichat, Paris, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>2 Université Paris Diderot, Sorbonne Paris Cité, Département Hospitalo-universitaire FIRE (Fibrosis, Inflammation and Remodeling) and LabEx Inflamex, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Menou</LastName>
<ForeName>Awen</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>1 Inserm UMR1152, Medical School Xavier Bichat, Paris, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>2 Université Paris Diderot, Sorbonne Paris Cité, Département Hospitalo-universitaire FIRE (Fibrosis, Inflammation and Remodeling) and LabEx Inflamex, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>François</LastName>
<ForeName>Charlène</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>1 Inserm UMR1152, Medical School Xavier Bichat, Paris, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>2 Université Paris Diderot, Sorbonne Paris Cité, Département Hospitalo-universitaire FIRE (Fibrosis, Inflammation and Remodeling) and LabEx Inflamex, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Duitman</LastName>
<ForeName>Jan Willem</ForeName>
<Initials>JW</Initials>
<AffiliationInfo><Affiliation>3 Center for Experimental and Molecular Medicine, Academic Medical Center, Amsterdam, the Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>von der Thüsen</LastName>
<ForeName>Jan H</ForeName>
<Initials>JH</Initials>
<AffiliationInfo><Affiliation>4 Department of Pathology, Erasmus Medical Centre, Rotterdam, the Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Borie</LastName>
<ForeName>Raphaël</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>2 Université Paris Diderot, Sorbonne Paris Cité, Département Hospitalo-universitaire FIRE (Fibrosis, Inflammation and Remodeling) and LabEx Inflamex, Paris, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>5 Assistance Publique-Hôpitaux de Paris, Department of Pulmonology A, Competence Center for Rare Lung Diseases, Bichat-Claude Bernard University Hospital, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sales</LastName>
<ForeName>Katiuchia Uzzun</ForeName>
<Initials>KU</Initials>
<AffiliationInfo><Affiliation>6 Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>7 Department of Cell and Molecular Biology, Ribeirão Preto School of Medicine, University of São Paulo Ribeirão Preto, São Paulo, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mutze</LastName>
<ForeName>Kathrin</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>8 Member of the German Center of Lung Research, Comprehensive Pneumology Center, University Hospital, Ludwig-Maximilians University, Helmholtz Zentrum München, Munich, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Castier</LastName>
<ForeName>Yves</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>9 Assistance Publique-Hôpitaux de Paris, Department of Vascular and Thoracic Surgery, Bichat-Claude Bernard University Hospital, Denis Diderot University and Medical School Paris VII, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sage</LastName>
<ForeName>Edouard</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>10 Department of Thoracic Surgery and Lung Transplantation, Hôpital Foch, Suresnes, France; and.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Ligong</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>11 Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bugge</LastName>
<ForeName>Thomas H</ForeName>
<Initials>TH</Initials>
<AffiliationInfo><Affiliation>6 Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fairlie</LastName>
<ForeName>David P</ForeName>
<Initials>DP</Initials>
<AffiliationInfo><Affiliation>11 Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Königshoff</LastName>
<ForeName>Mélanie</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>8 Member of the German Center of Lung Research, Comprehensive Pneumology Center, University Hospital, Ludwig-Maximilians University, Helmholtz Zentrum München, Munich, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Crestani</LastName>
<ForeName>Bruno</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>1 Inserm UMR1152, Medical School Xavier Bichat, Paris, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>2 Université Paris Diderot, Sorbonne Paris Cité, Département Hospitalo-universitaire FIRE (Fibrosis, Inflammation and Remodeling) and LabEx Inflamex, Paris, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>5 Assistance Publique-Hôpitaux de Paris, Department of Pulmonology A, Competence Center for Rare Lung Diseases, Bichat-Claude Bernard University Hospital, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Borensztajn</LastName>
<ForeName>Keren S</ForeName>
<Initials>KS</Initials>
<AffiliationInfo><Affiliation>1 Inserm UMR1152, Medical School Xavier Bichat, Paris, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>2 Université Paris Diderot, Sorbonne Paris Cité, Département Hospitalo-universitaire FIRE (Fibrosis, Inflammation and Remodeling) and LabEx Inflamex, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><Agency>Intramural NIH HHS</Agency>
<Country>United States</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D052060">Research Support, N.I.H., Intramural</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Am J Respir Crit Care Med</MedlineTA>
<NlmUniqueID>9421642</NlmUniqueID>
<ISSNLinking>1073-449X</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>EC 3.4.-</RegistryNumber>
<NameOfSubstance UI="D057057">Serine Proteases</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 3.4.21.-</RegistryNumber>
<NameOfSubstance UI="D012697">Serine Endopeptidases</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 3.4.21.-</RegistryNumber>
<NameOfSubstance UI="C485595">matriptase</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>AIM</CitationSubset>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Am J Respir Crit Care Med. 2016 Apr 15;193(8):816-7</RefSource>
<PMID Version="1">27082530</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Gastroenterology. 2001 Jun;120(7):1784-800</RefSource>
<PMID Version="1">11375959</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Nat Genet. 2010 Aug;42(8):676-83</RefSource>
<PMID Version="1">20657595</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Respir Crit Care Med. 2011 Mar 15;183(6):759-66</RefSource>
<PMID Version="1">20935114</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Acta Biomater. 2010 Aug;6(8):3146-51</RefSource>
<PMID Version="1">20144751</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Clin Immunol Immunopathol. 1994 Sep;72(3):283-92</RefSource>
<PMID Version="1">7914840</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Genes Dev. 2005 Aug 15;19(16):1934-50</RefSource>
<PMID Version="1">16103220</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>BMC Cancer. 2006;6:176</RefSource>
<PMID Version="1">16820046</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Eur Respir J. 2008 Aug;32(2):426-36</RefSource>
<PMID Version="1">18321937</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Oncogene. 2002 May 23;21(23):3765-79</RefSource>
<PMID Version="1">12032844</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>N Engl J Med. 2014 May 29;370(22):2083-92</RefSource>
<PMID Version="1">24836312</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Nutr Sci Vitaminol (Tokyo). 2003 Feb;49(1):27-32</RefSource>
<PMID Version="1">12882393</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Physiol Lung Cell Mol Physiol. 2014 Dec 1;307(11):L838-47</RefSource>
<PMID Version="1">25260753</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Respir Med. 2013 Feb;107(2):256-62</RefSource>
<PMID Version="1">23131707</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Chest. 2013 Jul;144(1):200-7</RefSource>
<PMID Version="1">23412700</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Biol Chem. 2007 Dec 14;282(50):36714-23</RefSource>
<PMID Version="1">17940283</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Biol Chem. 2013 Dec 27;288(52):37319-31</RefSource>
<PMID Version="1">24253040</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4200-5</RefSource>
<PMID Version="1">20142489</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Biol Chem. 2000 Nov 24;275(47):36720-5</RefSource>
<PMID Version="1">10962009</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>FASEB J. 2012 Jul;26(7):2877-87</RefSource>
<PMID Version="1">22467762</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Exp Med. 2011 Jul 4;208(7):1339-50</RefSource>
<PMID Version="1">21727191</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Annu Rev Cell Dev Biol. 2011;27:213-35</RefSource>
<PMID Version="1">21721945</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>FEBS Lett. 2002 Jul 17;523(1-3):85-9</RefSource>
<PMID Version="1">12123809</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Gastroenterol Hepatol. 2005 Jun;20(6):895-9</RefSource>
<PMID Version="1">15946137</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):769-75</RefSource>
<PMID Version="1">17255532</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Physiol Renal Physiol. 2013 Jul 15;305(2):F173-81</RefSource>
<PMID Version="1">23698112</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Bone. 2012 Mar;50(3):704-12</RefSource>
<PMID Version="1">22173052</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>N Engl J Med. 2014 May 29;370(22):2071-82</RefSource>
<PMID Version="1">24836310</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Respir Crit Care Med. 2011 Jun 15;183(12):1703-14</RefSource>
<PMID Version="1">21471103</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lancet. 2012 Aug 18;380(9842):680-8</RefSource>
<PMID Version="1">22901889</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lancet. 2011 Dec 3;378(9807):1949-61</RefSource>
<PMID Version="1">21719092</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lab Invest. 2005 Jan;85(1):75-89</RefSource>
<PMID Version="1">15531908</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Histochem Cytochem. 2003 Aug;51(8):1017-25</RefSource>
<PMID Version="1">12871983</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Transl Oncol. 2014 Oct;7(5):650-5</RefSource>
<PMID Version="1">24935008</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Oncogene. 2015 Jan 15;34(3):346-56</RefSource>
<PMID Version="1">24469043</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Front Biosci. 2004 Jan 1;9:283-9</RefSource>
<PMID Version="1">14766366</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lancet Respir Med. 2014 Nov;2(11):933-42</RefSource>
<PMID Version="1">25439569</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Hum Cell. 2015 Jan;28(1):44-50</RefSource>
<PMID Version="1">25186085</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Int J Biochem Cell Biol. 2008;40(6-7):1379-88</RefSource>
<PMID Version="1">18077203</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Oncogene. 2011 Apr 28;30(17):2003-16</RefSource>
<PMID Version="1">21217780</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Pharmacol Exp Ther. 2009 May;329(2):764-74</RefSource>
<PMID Version="1">19190233</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Physiol Lung Cell Mol Physiol. 2005 May;288(5):L793-802</RefSource>
<PMID Version="1">15563688</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Nature. 2012 Mar 29;483(7391):603-7</RefSource>
<PMID Version="1">22460905</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Proc Am Thorac Soc. 2012 Jul;9(3):111-6</RefSource>
<PMID Version="1">22802283</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Hum Immunol. 2013 Oct;74(10):1346-51</RefSource>
<PMID Version="1">23911740</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Pancreas. 2005 Jan;30(1):54-61</RefSource>
<PMID Version="1">15632700</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Pathol. 2010 Dec;177(6):2753-64</RefSource>
<PMID Version="1">20971733</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Arthritis Rheum. 2010 Jul;62(7):1955-66</RefSource>
<PMID Version="1">20506309</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trends Mol Med. 2008 Oct;14(10):429-40</RefSource>
<PMID Version="1">18774340</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Physiol Renal Physiol. 2012 Oct 15;303(8):F1126-35</RefSource>
<PMID Version="1">22832926</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Respir Crit Care Med. 2006 Jul 1;174(1):58-66</RefSource>
<PMID Version="1">16574935</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Thorax. 2010 Jan;65(1):70-6</RefSource>
<PMID Version="1">19996344</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Life Sci. 2007 May 1;80(21):1999-2004</RefSource>
<PMID Version="1">17433371</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Pancreas. 1998 Apr;16(3):427-31</RefSource>
<PMID Version="1">9548690</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Hepatology. 2012 Mar;55(3):879-87</RefSource>
<PMID Version="1">22095855</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015153" MajorTopicYN="N">Blotting, Western</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004195" MajorTopicYN="N">Disease Models, Animal</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D054990" MajorTopicYN="N">Idiopathic Pulmonary Fibrosis</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008168" MajorTopicYN="N">Lung</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D051379" MajorTopicYN="N">Mice</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008810" MajorTopicYN="N">Mice, Inbred C57BL</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016133" MajorTopicYN="N">Polymerase Chain Reaction</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012697" MajorTopicYN="N">Serine Endopeptidases</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D057057" MajorTopicYN="N">Serine Proteases</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
</MeshHeadingList>
<OtherID Source="NLM">PMC4849177 [Available on 04/15/17]</OtherID>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">camostat mesilate</Keyword>
<Keyword MajorTopicYN="N">fibroblast</Keyword>
<Keyword MajorTopicYN="N">idiopathic pulmonary fibrosis</Keyword>
<Keyword MajorTopicYN="N">matriptase</Keyword>
<Keyword MajorTopicYN="N">protease-activated receptor-2</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2015</Year>
<Month>11</Month>
<Day>25</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2015</Year>
<Month>11</Month>
<Day>26</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2016</Year>
<Month>9</Month>
<Day>1</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">26599507</ArticleId>
<ArticleId IdType="doi">10.1164/rccm.201502-0299OC</ArticleId>
<ArticleId IdType="pmc">PMC4849177</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/PubMed/Curation

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002056 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 002056 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
   |flux=    PubMed
   |étape=   Curation
   |type=    RBID
   |clé=     pubmed:26599507
   |texte=   Membrane-anchored Serine Protease Matriptase Is a Trigger of Pulmonary Fibrogenesis.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i   -Sk "pubmed:26599507" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd   \
       | NlmPubMed2Wicri -a AustralieFrV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024

	Serveur d'exploration sur les relations entre la France et l'Australie
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur les relations entre la France et l'Australie

Membrane-anchored Serine Protease Matriptase Is a Trigger of Pulmonary Fibrogenesis.

Membrane-anchored Serine Protease Matriptase Is a Trigger of Pulmonary Fibrogenesis.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Curation

No country items

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki